Angela M. Crawley, PhD, is a Senior Scientist at The Ottawa Hospital Research Institute, and an Associate Professor at the University of Ottawa. Her primary research program specializes in the study of immune dysfunction in chronic liver disease to identify immune-restorative targets. Her research program is focused on investigating the underlying mechanisms of immune cell dysfunction using high throughput cell culture and multi-parametric analytical methods. She integrates immunoassays of immune cell function with clinical data in established partnerships with clinician scientists in a translational research approach. Research using primary human specimens is complemented by the development of relevant animal models of liver disease. She facilitates basic science and clinical collaborations with colleagues in the Center for Liver of Eastern Ontario, offering laboratory research opportunities and biobanking of specimens as a shared resource.
Dr. Crawley is also the Director of the Canadian Biobank Alliance (CBA), which emerged in the recent pandemic from the Coronavirus Variants Rapid Response Network (CoVaRR-Net) in April 2021. With groundbreaking strides, the CBA has develope frameworks for the rapid, efficient sharing of biological materials and data across Canada. The development of a CBA metabase will catalog specimens from thousands of Canadians, many collected longitudinally, contributing to vital research. A passionate advocate for equity, diversity, inclusion, and Indigeneity, Dr. Crawley and colleagues in the CBA are working to remove barriers to fair and ethical sharing of biological materials and data.