Dr O’Kane completed her medical and oncology training in Ireland prior to commencing a fellowship in GI/thoracic oncology at the Princess Margaret Cancer Centre in Toronto in 2016. She joined faculty as a Clinician Investigator and Assistant Professor at The University of Toronto in 2019 specialising in liver and pancreatic cancers. Her primary research has been in integrative molecular profiling of tumours for biomarker development and she is PI of a number of investigator initiated studies in HPB malignancies. In particular her
work focusses on cancer subtypes utilizing RNA gene signatures and in immune checkpoint inhibitor combinations prior to surgery and transplantation for liver cancers. Dr O’Kane’s translational research has resulted in a number of awards from ASCO, ESMO and AACR and she has published over 130 manuscripts in peer reviewed journals.